Publications

17) Rosenbaum, J.C., and A.E. Carlson. Studying metal-protein interactions using fluorescent protein indicators. [Pre-print] bioRxiv ID: 2022.10.13.512174

16) Phelps, W.A., M.D. Hurton, T.N. Ayers, A.E. Carlson, J.C. Rosenbaum, and M.T. Lee. Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis. eLife: e83952 PMID 37787392

15) Komondor, K.M., R.E. Bainbridge, K.G. Sharp, J.C. Rosenbaum, and A.E. Carlson. 2023. TMEM16A activation for the fast block to polyspermy in the African clawed frog does not require conventional activation of egg PLCs. Journal of General Physiology. 155(10): e202213258 PMID 37561060

14) Tembo, M., C. Lara-Santos (co-first author), J.C. Rosenbaum, and A.E. Carlson. PIP2 and Ca2+ regulation of TMEM16A currents in excised inside-out patches [Pre-print] bioRxiv ID: 2022.08.30.505925

13) Tembo, M., R.E. Bainbridge, C. Lara-Santos, K.M. Komondor, G.J. Daskivich, J.D. Durrant, J.C. Rosenbaum, and A.E. Carlson. 2022. Phosphate position is key in mediating the transmembrane ion channel TMEM16A-phosphatidylinositol 4, 5-bisphosphate interaction. Journal of Biological Chemistry. 298(8): 102264 PMID 35843309

12) Lamade, A.M., L. Wu, H.H. Dar, H.L. Mentrup, I.H. Shrivasta, M.V. Epperly, C.M. St Croix, Y.Y. Tyurin, T.S. Anthonymuthu, Q. Yang, A.A. Kapralov, Z. Huang, G. Mao, A.A. Amoscato, Z.E. Hier, M.A. Artykhova, G. Shurin, J.C. Rosenbaum, P.J. Gough, J. Bertin, A.P VanDemark, S.C. Watkins, K.P. Mollen, I. Bahar, J.S. Greenberger, V.E. Kagan, M.J. Whalen, H. Bayir.. 2022. Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death. Redox Biology 50, 102232. PMID 35101798

11) Zhao, J., H.H. Dar, Y. Deng, C.M. St Croix, Z. Li, Y. Minami, I.H. Shrivastava, Y.Y. Tyurina, E. Etling, J.C. Rosenbaum, T. Nagasaki, J.B. Trudeau, S.C. Watkins, I. Bahar, H. Bayir, A.P. VanDemark, V.E. Kagan, S.E. Wenzel. 2020. PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells. Proceedings of the National Academy of Sciences 117 (25), 14376-14385. PMID 32513718

10) Rosenbaum, J.C., B. Bonilla, S.R. Hengel, T.M. Mertz, B.W. Herken., H.G. Kazemier, CA. Pressimone, T.C. Ratterman, E. MacNary, A. De Magis, Y. Kwon, S.K. Godin, B. Van Houten, D.P. Normolle, P. Sung, S.R. Das, K. Paeschke, S.A. Roberts, A.P. VanDemark, K.A. Bernstein. 2019. The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. Nature Communications 10 (1), 1-11. PMID 31383866

9) Anthonymuthu, T.S., E.M. Kenny, I. Shrivastava, Y.Y. Tyurina, Z.E. Hier, H.C. Ting, H.H. Dar, V.A. Tyurin, A. Nesterova, A.A. Amoscato, K. Mikulska-Ruminska, J.C. Rosenbaum, G. Mao, J. Zhao, M. Conrad, J.A. Kellum, S.E. Wenzel, A.P. VanDemark, I. Bahar, V.E. Kagan, H. Bayir. 2018. Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE. Journal of the American Chemical Society 140 (51), 17835-17839 PMID 30525572

8) Wenzel, S.E., Y.Y. Tyurina, J. Zhao, CM. St Croix, H.H. Dar, G. Mao, V.A. Tyurin, T.S. Anthonymuthu, A.A. Kapralov, A.A. Amoscato, K. Mikulska-Ruminska, I.H. Shrivasta, E.M. Kenny, Q. Yang, J.C. Rosenbaum, L.J. Sparvero, D.R. Emlet, X. Wen, Y. Minami, F. Qu, S.C. Watkins, T.R. Holman, A.P. VanDemark, J.A. Kellum, I. Vahar, H. Vayir, V.E. Kagan. 2017. PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals. Cell 171 (3), 628-641. PMID 29053969

7) Gu, S., W.W. Chan, G. Mohi, J.C. Rosenbaum, A. Zayad, Z. Lu, C. Virtanen, S. Li, B.G. Neel, R.A. Van Etten. 2016. Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1. Blood 127 (14), 1803-1813. PMID 26773044

6) Delbecq, S.P, J.C. Rosenbaum, and R.E. Klevit. 2015. A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers. Biochemistry 54 (28), 4276-4284

5) DeBerg, H.A., J.R. Bankston, J.C. Rosenbaum, P.S. Brzovic, W.N. Zagotta, S. Stoll. 2015. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure 23 (4), 734-744 PMID 25800552

4) Carlson, A.E., J.C. Rosenbaum, T.I Brelidze, R.E. Klevit, and W.N. Zagotta. 2013. Fisetin potentiates HCN2 channels. Journal of Biological Chemistry 288: 33136-45. PMC3831264

3) Rosenbaum, J.C., E.K. Fredrickson, M.L. Oeser, C.M. Garrett-Engele, M.N. Locke, L.A. Richardson, Z.W. Nelson, E.D. Hetrick, T.I. Milack, D.E. Gottschling, R.G. Gardner. 2011. Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates. Molecular Cell 41 (1), 93-106. PMID 21211726

2) E.K. Fredrickson, J.C. Rosenbaum (co-first author), M.N. Locke, T.I. Milac, R.G. Gardner. 2011. Exposed hydrophobicity is a key determinant of nuclear quality control degradation. Molecular Biology of the Cell 22 (13), 2384-2395. PMID 21551067

1) Rosenbaum, J.C., and R.G. Gardner. 2011. How a disordered ubiquitin ligase maintains order in nuclear protein homeostasis. Nucleus 2 (4), 93-106. PMID 21941105